Variety selection is one of the most important decisions a cotton producer will make. The variety and its associated traits set the stage for harvest at the time of planting. All other input decisions affect the performance of the variety selected. Since the introduction of transgenic cottons and the accompanying increases in seed costs and associated technology fees, variety selection has become increasingly important. Seed selection is the one decision that is not influenced by environmental factors. Therefore, choosing a high-yielding variety with acceptable fiber quality that is adapted to local growing conditions should be considered carefully because of the tremendous importance the decision plays for the entire season.